| 2015-10-30 19:00:00October 30, 2015 | Conrad Weiser vs Muhlenberg | 28 - 17 | Muhlenberg | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Daniel Boone vs Hazleton | 0 - 35 | Hazleton | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Governor Mifflin vs Exeter | 21 - 35 | Exeter | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Berks Catholic vs Kutztown | 58 - 6 | Kutztown | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Twin Valley vs Fleetwood | 46 - 6 | Fleetwood | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Hamburg vs Pequea Valley | 21 - 27 | Pequea Valley | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Reading vs Pottsville | 14 - 34 | Pottsville | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Wyomissing vs Schuylkill Valley | 35 - 7 | Schuylkill Valley | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Archbishop Wood vs Archbishop Carroll | 54 - 0 | Conshy A Field | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Cardinal O’Hara vs Bonner-Prendergast | 0 - 20 | Bonner-Prendergast | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Father Judge vs LaSalle College Prep | 14 - 41 | LaSalle College Prep | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Bensalem vs Abington | 35 - 36 | Abington | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Boyertown vs Phoenixville | 49 - 35 | Phoenixville | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Conestoga vs Garnet Valley | 7 - 14 | Garnet Valley | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Council Rock North vs Quakertown | 41 - 31 | Quakertown | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Delco Christian vs Morrisville | 36 - 20 | Morrisville | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Downingtown East vs West Chester East | 45 - 0 | West Chester East | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Downingtown West vs Avon Grove | 54 - 14 | Avon Grove | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Great Valley vs West Chester Henderson | 34 - 14 | West Chester Henderson | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Hatboro-Horsham vs Upper Dublin | 10 - 31 | Upper Dublin | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Haverford vs Ridley | 21 - 13 | Ridley | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Marple Newtown vs Penncrest | 20 - 17 | Penncrest | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Oxford vs Kennett | 48 - 21 | Kennett | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Penn Wood vs Glen Mills | 21 - 41 | Glen Mills | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Pennridge vs Souderton | 14 - 8 | Souderton | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Pennsbury vs Central Bucks South | 27 - 9 | Central Bucks South | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Plymouth-Whitemarsh vs Cheltenham | 35 - 14 | Cheltenham | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Pottsgrove vs Owen J. Roberts | 47 - 3 | Owen J. Roberts | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Springfield-Delco vs Harriton | 63 - 6 | Harriton | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Unionville vs Octorara | 46 - 12 | Octorara | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Upper Merion vs Wissahickon | 18 - 6 | Wissahickon | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Upper Moreland vs Springfield-Montco | 62 - 14 | Springfield-Montco | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Upper Perkiomen vs Perkiomen Valley | 0 - 45 | Perkiomen Valley | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Valley Forge Military Academy vs Bristol | 13 - 46 | Bristol | Recap |
| 2015-10-30 19:00:00October 30, 2015 | West Chester Rustin vs Sun Valley | 41 - 7 | Sun Valley | Recap |
| 2015-10-30 19:00:00October 30, 2015 | William Tennent vs Harry S. Truman | 20 - 53 | Harry S. Truman | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Chichester vs Interboro | 7 - 41 | Interboro | Recap |
| 2015-10-30 19:00:00October 30, 2015 | Radnor vs Strath Haven | 40 - 12 | Strath Haven | Recap |
| 2015-10-30 19:30:00October 30, 2015 | Neshaminy vs North Penn | 17 - 22 | North Penn | Recap |
| 2015-10-31 10:30:00October 31, 2015 | Academy Park vs Chester | 28 - 6 | Chester | Recap |
| 2015-10-31 11:00:18October 31, 2015 | Episcopal Academy vs William Penn Charter | 35 - 42 | William Penn Charter | Recap |
| 2015-10-31 13:00:00October 31, 2015 | Central Bucks West vs Central Bucks East | 16 - 42 | Central Bucks East | Recap |
| 2015-10-31 13:00:00October 31, 2015 | West Catholic vs Archbishop Ryan | 35 - 38 | Washington | Recap |
| 2015-10-31 13:00:00October 31, 2015 | Coatesville vs Bishop Shanahan | 23 - 14 | Bishop Shanahan | Recap |
| 2015-10-31 13:00:00October 31, 2015 | Council Rock South vs Norristown | 49 - 45 | Norristown | Recap |
| 2015-10-31 13:00:00October 31, 2015 | Methacton vs Pottstown | 14 - 40 | Pottstown | Recap |
| 2015-10-31 13:00:00October 31, 2015 | Spring-Ford vs Pope John Paul II | 56 - 0 | Pope John Paul II | Recap |
| 2015-10-31 13:00:00October 31, 2015 | Upper Darby vs Lower Merion | 49 - 0 | Lower Merion | Recap |
| 2015-10-31 13:00:42October 31, 2015 | Haverford School vs Springside-Chestnut Hill | 45 - 14 | | Recap |
| 2015-10-31 13:30:00October 31, 2015 | Malvern Prep vs Germantown Academy | 34 - 7 | Germantown Academy | Recap |
| 2015-10-31 13:30:57October 31, 2015 | Jenkintown vs. Lower Moreland | 39 - 7 | Lower Moreland | Recap |
| 2015-10-31 14:00:00October 31, 2015 | New Hope-Solebury vs George School | 48 - 14 | George School | Recap |
| 2015-10-31 18:00:00October 31, 2015 | Neumann-Goretti vs Lansdale Catholic | 6 - 42 | SP Super Site | Recap |
| 2015-10-31 19:00:00October 31, 2015 | Roman Catholic vs St. Joseph's Prep | 7 - 41 | Plymouth-Whitemarsh | Recap |
| 2015-10-31 19:00:00October 31, 2015 | Conwell-Egan vs Bishop McDevitt | 31 - 20 | Cheltenham | Recap |
| 2015-10-31 19:21:13October 31, 2015 | Mercersburg Academy vs Hill School | 29 - 60 | | Recap |
