| 2015-11-20 13:22:12November 20, 2015 | Exeter vs. Cumberland Valley | 17 - 35 | | Recap |
| 2015-11-20 13:23:54November 20, 2015 | Reading vs. Emmaus | 13 - 56 | | Recap |
| 2015-11-20 19:00:00November 20, 2015 | Delco Christian vs Bishop McDevitt | 9 - 21 | | Recap |
| 2015-11-20 19:00:00November 20, 2015 | New Hope-Solebury vs Springfield-Montco | 14 - 7 | | Recap |
| 2015-11-20 19:00:00November 20, 2015 | Academy Park vs Great Valley | 39 - 14 | | Recap |
| 2015-11-20 19:00:00November 20, 2015 | Upper Moreland vs Marple Newtown | 28 - 20 | | Recap |
| 2015-11-20 19:00:00November 20, 2015 | North Penn vs Downingtown East | 27 - 14 | Downingtown East | Recap |
| 2015-11-20 19:00:00November 20, 2015 | Neshaminy vs Quakertown | 31 - 17 | | Recap |
| 2015-11-20 19:00:00November 20, 2015 | Pennsbury vs Perkiomen Valley | 41 - 28 | | Recap |
| 2015-11-20 19:00:00November 20, 2015 | Upper Dublin vs Upper Darby | 45 - 14 | | Recap |
| 2015-11-20 19:00:11November 20, 2015 | Archbishop Ryan vs Archbishop Wood | 7 - 35 | William Tennent | Recap |
| 2015-11-21 13:00:45November 21, 2015 | LaSalle College Prep vs St. Joseph’s Prep | 29 - 28 | Plymouth-Whitemarsh | Recap |
| 2015-11-21 18:12:15November 21, 2015 | Archbishop Carroll vs Norristown | 20 - 7 | | Recap |
| 2015-11-21 20:09:50November 21, 2015 | Delaware Valley Charter vs. West Catholic | 18 - 28 | | Recap |
| 2015-11-25 18:00:00November 25, 2015 | South Hunterdon Regional (NJ) vs New Hope-Solebury | 7 - 14 | New Hope-Solebury | Recap |
| 2015-11-25 19:00:57November 25, 2015 | Malvern Prep vs Cardinal O'Hara | 49 - 7 | Cardinal O'Hara | Recap |
| 2015-11-26 10:00:00November 26, 2015 | Father Judge vs Abraham Lincoln | 35 - 14 | Abraham Lincoln | Recap |
| 2015-11-26 10:00:00November 26, 2015 | Harry S. Truman vs Conwell-Egan | 18 - 17 | Conwell-Egan | Recap |
| 2015-11-26 10:00:00November 26, 2015 | Owen J. Roberts vs Pottstown | 41 - 13 | Pottstown | Recap |
| 2015-11-26 10:00:17November 26, 2015 | Interboro vs Ridley | 0 - 12 | Ridley | Recap |
| 2015-11-26 10:00:33November 26, 2015 | Archbishop Ryan vs Washington | 35 - 7 | | Recap |
| 2015-11-26 10:00:51November 26, 2015 | Abington vs Cheltenham | 36 - 41 | Cheltenham | Recap |
| 2015-11-26 10:15:00November 26, 2015 | Quakertown vs Pennridge | 28 - 21 | Pennridge | Recap |
| 2015-11-26 10:30:00November 26, 2015 | Chichester vs Sun Valley | 7 - 20 | Sun Valley | Recap |
| 2015-11-26 10:30:00November 26, 2015 | Morrisville vs Bristol | 0 - 38 | Bristol | Recap |
| 2015-11-26 10:30:00November 26, 2015 | Neumann-Goretti vs South Philadelphia | 26 - 24 | South Philadelphia | Recap |
| 2015-11-26 10:30:00November 26, 2015 | Roman Catholic vs Roxborough | 49 - 6 | | Recap |
| 2015-11-26 10:45:00November 26, 2015 | Upper Darby vs Haverford | 42 - 49 | Haverford | Recap |
| 2015-11-26 17:09:32November 26, 2015 | Norristown vs. Upper Merion | 21 - 33 | | Recap |
