| 2021-04-06 15:45:00April 6, 2021 | Boyertown vs Methacton | 9 - 15 | Recap |
| 2021-04-06 15:45:00April 6, 2021 | Upper Merion vs Pottsgrove | 12 - 8 | Recap |
| 2021-04-09 15:45:00April 9, 2021 | Upper Merion vs Phoenixville | 8 - 7 | Recap |
| 2021-04-09 18:30:00April 9, 2021 | Owen J. Roberts vs Methacton | 4 - 5 | Recap |
| 2021-04-09 19:00:00April 9, 2021 | Spring-Ford vs Perkiomen Valley | 7 - 8 | Recap |
| 2021-04-13 15:45:00April 13, 2021 | Pope John Paul II vs Boyertown | 3 - 18 | Recap |
| 2021-04-13 19:00:00April 13, 2021 | Phoenixville vs Methacton | 3 - 11 | Recap |
| 2021-04-13 19:00:00April 13, 2021 | Pottsgrove vs Owen J. Roberts | 5 - 10 | Recap |
| 2021-04-13 19:15:00April 13, 2021 | Upper Merion vs Spring-Ford | 6 - 16 | Recap |
| 2021-04-15 15:45:00April 15, 2021 | Owen J. Roberts vs Pope John Paul II | 13 - 5 | Recap |
| 2021-04-15 15:45:00April 15, 2021 | Spring-Ford vs Phoenixville | 9 - 2 | Recap |
| 2021-04-15 19:00:00April 15, 2021 | Boyertown vs Perkiomen Valley | 1 - 12 | Recap |
| 2021-04-17 10:00:00April 17, 2021 | Pope John Paul II vs Spring-Ford | 4 - 17 | Recap |
| 2021-04-17 12:00:00April 17, 2021 | Perkiomen Valley vs Upper Merion | 15 - 2 | Recap |
| 2021-04-20 15:45:00April 20, 2021 | Upper Merion vs Boyertown | 10 - 15 | Recap |
| 2021-04-20 15:45:00April 20, 2021 | Pope John Paul II vs Methacton | 1 - 17 | Recap |
| 2021-04-20 15:45:00April 20, 2021 | Phoenixville vs Pottsgrove | 5 - 4 | Recap |
| 2021-04-20 19:00:00April 20, 2021 | Perkiomen Valley vs Owen J. Roberts | 13 - 4 | Recap |
| 2021-04-22 15:45:00April 22, 2021 | Boyertown vs Spring-Ford | 5 - 15 | Recap |
| 2021-04-22 15:45:00April 22, 2021 | Pottsgrove vs Pope John Paul II | 7 - 8 | Recap |
| 2021-04-22 18:45:00April 22, 2021 | Owen J. Roberts vs Upper Merion | 6 - 7 | Recap |
| 2021-04-23 15:45:00April 23, 2021 | Spring-Ford vs Pottsgrove | 15 - 4 | Recap |
| 2021-04-23 15:45:00April 23, 2021 | Interboro vs Pope John Paul II | 12 - 11 | Recap |
| 2021-04-23 19:00:00April 23, 2021 | Methacton vs Perkiomen Valley | 6 - 7 | Recap |
| 2021-04-26 19:30:00April 26, 2021 | Owen J. Roberts vs Boyertown | 7 - 8 | Recap |
| 2021-04-27 15:45:00April 27, 2021 | Interboro vs Boyertown | 8 - 17 | Recap |
| 2021-04-27 15:45:00April 27, 2021 | Perkiomen Valley vs Pottsgrove | 18 - 5 | Recap |
| 2021-04-27 15:45:00April 27, 2021 | Phoenixville vs Pope John Paul II | 7 - 6 | Recap |
| 2021-04-27 18:30:00April 27, 2021 | Upper Merion vs Methacton | 11 - 20 | Recap |
| 2021-04-27 19:30:00April 27, 2021 | Spring-Ford vs Owen J. Roberts | 7 - 6 | Recap |
| 2021-04-28 15:45:00April 28, 2021 | Interboro vs Phoenixville | 6 - 7 | Recap |
| 2021-04-29 18:45:00April 29, 2021 | Pottsgrove vs Upper Merion | 7 - 20 | Recap |
| 2021-04-29 19:00:00April 29, 2021 | Pope John Paul II vs Perkiomen Valley | 1 - 16 | Recap |
| 2021-04-30 15:45:00April 30, 2021 | Methacton vs Pottsgrove | 17 - 4 | Recap |
| 2021-05-01 10:00:00May 1, 2021 | Perkiomen Valley vs Boyertown | 16 - 6 | Recap |
| 2021-05-01 12:00:00May 1, 2021 | Spring-Ford vs Springside-Chestnut Hill | 8 - 9 | Recap |
| 2021-05-01 18:45:00May 1, 2021 | Interboro vs Upper Merion | 9 - 15 | Recap |
| 2021-05-03 15:45:00May 3, 2021 | Boyertown vs Pottsgrove | 18 - 9 | Recap |
| 2021-05-03 19:00:00May 3, 2021 | Phoenixville vs Perkiomen Valley | 5 - 18 | Recap |
| 2021-05-04 15:45:00May 4, 2021 | Upper Merion vs Pope John Paul II | 17 - 5 | Recap |
| 2021-05-04 17:00:00May 4, 2021 | Spring-Ford vs Allentown Central Catholic | 3 - 14 | Recap |
| 2021-05-04 19:00:00May 4, 2021 | Boyertown vs Owen J. Roberts | 8 - 12 | Recap |
| 2021-05-04 19:00:00May 4, 2021 | Interboro vs Methacton | 2 - 17 | Recap |
| 2021-05-05 17:45:00May 5, 2021 | Perkiomen Valley vs Interboro | 17 - 1 | Recap |
| 2021-05-06 15:45:00May 6, 2021 | Pottsgrove vs Interboro | 10 - 5 | Recap |
| 2021-05-06 15:45:00May 6, 2021 | Upper Merion vs Conwell-Egan | 13 - 2 | Recap |
| 2021-05-06 19:00:00May 6, 2021 | Owen J. Roberts vs Phoenixville | 12 - 4 | Recap |
| 2021-05-06 19:00:00May 6, 2021 | Governor Mifflin vs Spring-Ford | 8 - 15 | Recap |
| 2021-05-06 19:30:00May 6, 2021 | Methacton vs Boyertown | 15 - 7 | Recap |
| 2021-05-07 17:30:00May 7, 2021 | Methacton vs Spring-Ford | 5 - 9 | Recap |
| 2021-05-07 19:00:00May 7, 2021 | Emmaus vs Perkiomen Valley | 7 - 4 | Recap |
| 2021-05-08 11:00:00May 8, 2021 | Boyertown vs Daniel Boone | 12 - 2 | Recap |
| 2021-05-08 14:30:00May 8, 2021 | Perkiomen Valley vs Crestwood | 10 - 9 | Recap |
| 2021-05-08 14:30:00May 8, 2021 | Archbishop Carroll vs Upper Merion | 5 - 16 | Recap |
| 2021-05-10 15:45:00May 10, 2021 | Methacton vs Harriton | 10 - 6 | Recap |
| 2021-05-10 15:45:00May 10, 2021 | Sun Valley vs Pottsgrove | 4 - 17 | Recap |
| 2021-05-10 19:00:00May 10, 2021 | Boyertown vs Phoenixville | 14 - 11 | Recap |
| 2021-05-11 15:45:00May 11, 2021 | Archbishop Carroll vs Phoenixville | 8 - 7 | Recap |
| 2021-05-11 18:45:00May 11, 2021 | Devon Prep vs Upper Merion | 11 - 17 | Recap |
| 2021-05-11 19:00:00May 11, 2021 | Souderton vs Methacton | 1 - 14 | Recap |
| 2021-05-11 19:00:00May 11, 2021 | Owen J. Roberts vs Perkiomen Valley | 5 - 15 | Recap |
| 2021-05-12 15:45:00May 12, 2021 | Pennridge vs Boyertown | 14 - 13 | Recap |
| 2021-05-13 15:30:00May 13, 2021 | Methacton vs Upper Moreland | 11 - 6 | Recap |
| 2021-05-13 15:45:00May 13, 2021 | Phoenixville vs Lower Merion | 6 - 12 | Recap |
| 2021-05-13 17:30:00May 13, 2021 | Pottsgrove vs Upper Darby | 16 - 4 | Recap |
| 2021-05-13 18:00:00May 13, 2021 | Boyertown vs Quakertown | 16 - 2 | Recap |
| 2021-05-13 19:00:00May 13, 2021 | Haverford vs Perkiomen Valley | 9 - 10 | Recap |
| 2021-05-14 15:45:00May 14, 2021 | Methacton vs North Penn | 9 - 6 | Recap |
| 2021-05-14 15:45:00May 14, 2021 | Upper Merion vs Holy Ghost Prep | 6 - 5 | Recap |
| 2021-05-14 16:00:00May 14, 2021 | Pottsgrove vs Wyomissing | 9 - 7 | Recap |
Spring-Ford
Owen J. Roberts
Perkiomen Valley
Methacton
Boyertown
Upper Merion
Pope John Paul II
Pottsgrove
Interboro
Phoenixville
